This intensive one-week course covers various aspects of neuroimaging and genetics analyses. We will start with two parallel tracks that provide a brief introduction to both imaging and genetics. This makes the course interesting for people with either background. We will then move on to single genetic variant statistics for the different imaging modalities (structural imaging based on (sub)cortical volumetry and diffusion tensor imaging and brain activity and functional connectivity based on (resting state) fMRI). This will be followed by more advanced gene wide analyses, as well as genome wide approaches. Other important topics include the integration across levels of investigation and linking genetics to behaviour via the brain - the essence of Cognomics research. We will conclude with an outlook to multivariate genome-wide brain-wide analysis approaches.The lecture programme will be supplemented with hands on computer exercises and demonstrations. Evenings will be reserved for faculty lectures and for social activities.

Period
11-08-2014 - 15-08-2014 (1 weeks)

Target group
Students with a background in neuroimaging or genetics including:basic knowledge of brain anatomy and neurophysiologybasic knowledge of MRIbasic knowledge of statistics (GLM, regression, correlation) basic knowledge of the organization of the genomeThe school is directed at national and international graduate students and junior postdocs (max. 40) who wish to develop their knowledge and skills on state art developments in the field of neuroimaging genetics. The faculty includes researchers involved in the largest imaging genetics consortium world‐wide - the ENIGMA Consortium - and the Dutch Cognomics Program. Topics include brain volume and structural connectivity analysis, resting state functional MRI, combined with genetic information on various levels, new mass-univariate and multivariate analysis methods, and mediation analysis methods.

Course aim
After this course you will be able to:1. Prepare imaging and genetics data for imaging genetics analyses2. Perform analyses combining imaging and genetics data3. Determine whether the effects of a gene on behaviour are mediated by brain phenotypes



Credits
2.0 ECTS credits

Course fee
EUR 400[Convert to USD]The course fee includes the registration fee, course materials, access to library and IT facilities, coffee/tea, lunch, and a number of social activities. The fee does not include accommodation, travel costs, dinner, insurance and other costs. Discounts10% discount for early bird applicants. The early bird deadline is 1 April 2014.15% discount for students and PhD candidates from Radboud University and partner universities

Course leader
Prof. Dr. B. (Barbara) Franke, Chair of the Nijmegen Cognomics Initiative, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical centre

Radboud University
Address: P.O Box 9102 Nijmegen
Postal code: 6500 HC
City: Nijmegen
Country: Netherlands
Website: http://www.ru.nl/radboudsummerschool/
E-mail: radboudsummerschool@ru.nl
Phone: +31 (0)24 8187706