This course focuses on the chemical principles underlying protein structure and function and how proteins form an assembly of "molecular machines" that work together to sustain the living state. We will explore how proteins "know" what shape they should fold up into following their synthesis, how they cluster into dynamic macromolecular complexes, and how these complexes communicate to form "social" networks that enable cells to move, replicate, signal, and execute other vital processes.

The students will be introduced to advanced methods in structural and molecular biology for decoding the cellular protein machinery at atomic resolution, and examine how malfunction of specific components can lead to systemic failure and disease. The school will combine theory (lectures, tutorials) with experiment, laboratory tours and a visit to a leading Biotech company.

Period
19-08-2013 - 30-08-2013 (2 weeks)

Target group
Advanced bachelors / beginning masters in the early stage of their study with a background in chemistry, molecular biology or biophysics as well as proficiency in English.

Course aim
To introduce the student to technology for decoding natures molecular machines, and how the acquired knowledge provides a rationale for novel therapeutic interventions and applications in nano- and synthetic biology.

Credits
3.0 ECTS credits



Certificate of Attendance

Course fee
EUR 835: Course + course materials + housing

EUR 500: Course + course materials

Course leader
Dr. S.G.D. Rdiger

Scholarships
A limited number of scholarships in the form of (partial) fee waivers and/or accommodation intended for talented students from developing countries is available. Talented students from other countries can also apply. There are no travel grants.

Utrecht University
Address: PO BOX 80148
Postal code: 3508 TC
City: Utrecht
Country: Netherlands
Website: http://www.utrechtsummerschool.nl
E-mail: summerschool@uu.nl
Phone: 0031302534400